Status:

RECRUITING

Clinical Application of Quantitative Major Imaging Features of CEUS LI-RADS

Lead Sponsor:

Second Affiliated Hospital, School of Medicine, Zhejiang University

Conditions:

Liver Cancer

Eligibility:

All Genders

18+ years

Brief Summary

Liver cancer (LC) is the sixth most common malignant tumor and the third cause of cancer mortality in the world. According to the 2018 United States Association for the Study of Liver Diseases guideli...

Eligibility Criteria

Inclusion

  • High-risk groups of HCC: patients with liver cirrhosis or chronic viral hepatitis B, or patients who have been diagnosed with HCC or have a history of HCC in the past, as well as adult liver transplant patients and follow-up patients after liver transplantation;
  • CEUS and contrast-enhanced CT/MRI examinations were performed within 2 months before surgery;
  • There are clear surgical pathological or puncture pathological results;
  • Clinical, imaging, and pathological data are complete

Exclusion

  • Patients who are not suitable for LI-RADS: patients aged 18 years old or liver cirrhosis caused by congenital liver fibrosis or liver cirrhosis due to hepatovascular disease or diffuse regenerative nodules in the liver;
  • Those who underwent drug therapy (chemotherapy, immunotherapy, and targeted therapy) or local treatment of target lesions (TACE, radiotherapy, radiofrequency ablation, microwave ablation, etc.);
  • The quality of the patient's preoperative image or surgical pathological image is poor or incomplete;
  • Those with annular hyperenhancement or marginal nodular hyperenhancement of arterial lesions in contrast-enhanced ultrasound.

Key Trial Info

Start Date :

July 5 2024

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

July 1 2026

Estimated Enrollment :

50 Patients enrolled

Trial Details

Trial ID

NCT06590948

Start Date

July 5 2024

End Date

July 1 2026

Last Update

September 19 2024

Active Locations (1)

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Department of Ultrasound, Second Affiliated Hospital, School of Medicine, Zhejiang University

Hangzhou, Zhejiang, China, 310000