Status:
NOT_YET_RECRUITING
The Efficacy of Quadruple Therapy Containing Sodium Bicarbonate as the Primary Treatment for Helicobacter Pylori Infection
Lead Sponsor:
Second Affiliated Hospital, School of Medicine, Zhejiang University
Conditions:
Helicobacter Pylori Infection
Eligibility:
All Genders
18-65 years
Phase:
PHASE2
PHASE3
Brief Summary
The goal of this clinical trial is to learn the efficacy of sodium bicarbonate-containing quadruple therapy as the primary treatment for Helicobacter pylori infection. The main questions it aims to an...
Eligibility Criteria
Inclusion
- Aged 18-65 years, no history of eradication therapy;
- Diagnosed with Helicobacter pylori infection by one or more of the following methods: gastric mucosal histochemical staining, tissue culture, 14C-UBT, 13C-UBT and/or fecal antigen;
- Patients with warning symptoms, family history of gastric cancer or over 40 years old should undergo endoscopic examination before eradication therapy;
- Voluntarily participate in clinical trials and sign informed consent.
Exclusion
- Use of antibiotics or bismuth within 4 weeks before enrollment, or use of acid suppressants (including H2RA, PPI or P-CAB) within 2 weeks;
- Active peptic ulcer with complications such as bleeding, perforation or obstruction;
- History of esophagectomy or gastrectomy;
- Allergy to any study drug;
- Pregnancy or lactation;
- History of alcoholism or drug abuse;
- Mental illness;
- Incapacity for civil conduct.
Key Trial Info
Start Date :
September 15 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 30 2025
Estimated Enrollment :
855 Patients enrolled
Trial Details
Trial ID
NCT06591494
Start Date
September 15 2024
End Date
December 30 2025
Last Update
September 19 2024
Active Locations (0)
Enter a location and click search to find clinical trials sorted by distance.
No Results Found
We couldn’t find results for the location/zipcode entered or within the selected range. Please check your input or adjust your search.