Status:
COMPLETED
Oral Cryotherapy Applied to Patients Undergoing Chemotherapy
Lead Sponsor:
Karadeniz Technical University
Conditions:
Oncologic Disease
Cancer
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Taste alteration can cause problems such as loss of appetite, inadequate energy intake and weight loss in oncology patients, increasing the risk of malnutrition and negatively affecting the quality of...
Detailed Description
Taste changes disrupt the nutritional plan of patients, causing weight loss and an increased risk of malnutrition, and may negatively affect quality of life. However, this symptom is generally not con...
Eligibility Criteria
Inclusion
- Those receiving treatment in an outpatient chemotherapy unit,
- Able to communicate verbally,
- Literate,
- Eastern Cooperative Oncology Group (ECOG) Performance Score of two or below,
- Knowing their diagnosis,
- Taking five chemotherapeutic agents that cause taste changes, either alone or in combination (cisplatin, docetaxel, paclitaxel, oxaliplatin, vincristine),
- Verbally stating that they experience taste changes,
- Not smoking or quitting alcohol,
- Not using statins, hypothyroidism, antidiabetic, antipsychotic, hyperthyroidism, antidepressant, antihistamine, anti-inflammatory, antibiotic and antifungal drugs,
- Not having Chronic Renal Failure (CKD), metabolic (diabetes, thyroid disease, etc.) and liver (hepatitis, cirrhosis) diseases,
- Individuals who volunteered to participate in the study were included in the study.
Exclusion
- Patients who have had their treatment postponed at least twice in a row,
- Those with a World Health Organization Oral Toxicity Scale score of 1 and above,
- Those who have received radiotherapy to the head and neck region,
- Those with head/neck, stomach and liver cancer,
- Those who cannot be reached during phone calls,
- Those whose chemotherapy protocol has changed or who will be applied to a protocol other than the specified agents,
- Those with neutropenia (neutrophils; 1000 mcL and below),
- Those with tooth sensitivity,
- Those who have experienced a change in taste before starting the chemotherapy protocol\*\* and
- Those who do not want to continue the study will be excluded from the study.
Key Trial Info
Start Date :
July 1 2024
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 1 2025
Estimated Enrollment :
65 Patients enrolled
Trial Details
Trial ID
NCT06594354
Start Date
July 1 2024
End Date
June 1 2025
Last Update
June 19 2025
Active Locations (3)
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1
Recep Tayyip Erdogan University
Rize, Rize Province, Turkey (Türkiye), 53100
2
Recep Tayyip Erdoğan University Training and Research Hospital
Rize, Rize Province, Turkey (Türkiye), 53100
3
Recep Tayyip Erdoğan University
Rize, Rize Province, Turkey (Türkiye), 53100