Status:

RECRUITING

Investigating the Impact of Duration and Amount of Light on the Circadian System Response - Aim 3

Lead Sponsor:

Icahn School of Medicine at Mount Sinai

Collaborating Sponsors:

National Institute on Aging (NIA)

Conditions:

Alzheimer's Disease

Mild Cognitive Impairment

Eligibility:

All Genders

55+ years

Phase:

NA

Brief Summary

Investigate the long-term impact of amount and duration of Tailored Lighting Intervention (TLI) obtained from Aims 1 and 2 on sleep, cognition, circadian marker, mood, and behavior in AD/ADRD patients...

Eligibility Criteria

Inclusion

  • Diagnosis of Alzheimer's disease or related dementia with a Montreal Cognitive Assessment score \<25
  • Sleep disturbance with a Pittsburgh Sleep Quality Index score ≥5

Exclusion

  • Extensive brain vascular disease, traumatic brain injury, multiple sclerosis, Parkinson's Disease
  • Obstructing cataracts
  • Severe macular degeneration
  • Use of sleep medication
  • Use of oral melatonin
  • untreated moderate to severe sleep apnea
  • Severe restless leg syndrome - Blindness

Key Trial Info

Start Date :

December 3 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

January 31 2027

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT06595030

Start Date

December 3 2024

End Date

January 31 2027

Last Update

May 29 2025

Active Locations (2)

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Page 1 of 1 (2 locations)

1

Icahn School of Medicine at Mount Sinai

Menands, New York, United States, 12204

2

Icahn School of Medicine at Mount Sinai

New York, New York, United States, 10029

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