Status:
RECRUITING
Comparison Between Epidural Analgesia and Intrathecal Opioid Analgesia for Pain Management in Open Nephrectomy
Lead Sponsor:
University Hospital of Split
Conditions:
Pain
Renal Cancer
Eligibility:
All Genders
18+ years
Phase:
PHASE1
Brief Summary
Nephrectomy is a surgical procedure of choice for patients suffering from renal cell carcinoma (RCC). Even though the laparoscopic approach is considered to cause fewer complications and reduce hospit...
Detailed Description
This is a prospective, single-center, randomized controlled trial. The study will take place in the University Hospital of Split, Departments of Anesthesiology, Reanimatology and Intensive Care Medici...
Eligibility Criteria
Inclusion
- Adult patients over the age of 18, scheduled for an open radical or partial nephrectomy due to RCC.
- American Society of Anesthesiologists (ASA) physical status classification I-III.
Exclusion
- Patients who refuse to participate in this study.
- Patients with BMI \> 35 kg/m2 or \< 15 kg/m2.
- Patients with renal dysfunction (eGFR \<15 or requirement of renal replacement therapy), liver dysfunction (Child-Pugh class C), and heart failure (NYHA IV).
- Patients with ASA physical status classification ≥ IV.
- Patients with contraindication for the interventions planned for in this study (allergies to anesthetic drugs used in this study, coagulation disorders, and infection at the injection site).
- Patients with chronic opioid dependence.
- Patients unable to communicate preoperatively due to severe dementia, language barrier, or neuropsychiatric disorder.
- Patients for whom it is impossible to carry out the aforementioned interventions for technical reasons.
Key Trial Info
Start Date :
January 15 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2025
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT06595329
Start Date
January 15 2025
End Date
December 31 2025
Last Update
March 10 2025
Active Locations (1)
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1
Univeristy Hospital of Split
Split, Croatia, 21000