Status:
RECRUITING
Effects of Combined 40 Hz Audio-visual Stimulation and Cognitive Games on Alzheimer's Disease
Lead Sponsor:
Istanbul Medipol University Hospital
Collaborating Sponsors:
The Scientific and Technological Research Council of Turkey
Guven Health Group
Conditions:
Alzheimer's Disease
40 Hz Stimulation
Eligibility:
All Genders
60-86 years
Phase:
NA
Brief Summary
In addition to ongoing drug treatments for Alzheimer Disease (AD), protective approaches that can halt the progression of the disease are of particular importance. This project aims to develop a digit...
Detailed Description
This study aims to recruit early and middle-stage Alzheimer patients aged between 60 and 75, along with age and gender-matched healthy older adults. Two different Alzheimer groups will be created: one...
Eligibility Criteria
Inclusion
- Inclusion and Exclusion Criteria for Alzheimer Patients:
- Diagnosed with AD according to DSM-IV and NINCDS-ADRDA criteria,
- Impaired activities of daily living,
- Having a CDR score of 1-2 and an SMMT score of 15-26,
- Stable use of psychoactive medications, including acetylcholinesterase inhibitors or other medications that enhance cognitive functions,
- Individuals aged 60-86 with at least 5 years of education.
Exclusion
- Having frontotemporal dementia, vascular dementia, Lewy body dementia or other types of dementia,
- Parkinsonism, clinical depression, other mental disorders, epilepsy, drug addiction, alcohol addiction, and traumatic brain injury
- Inclusion and Exclusion Criteria of Healthy Older Adults:
- Inclusion criteria:
- Between the ages of 60-86
- Without any neurological abnormalities or general cognitive impairment (MMSE above 25),
- Not diagnosed with a neurological and/or psychiatric disease,
- Not using neurological and/or psychiatric medication
- Exclusion criteria
- Having clinical signs of cognitive impairment, such as mild cognitive impairment, Alzheimer disease, Parkinson disease, Lewy body dementia, frontotemporal dementia, etc.
- Epilepsy, alcohol and/or drug addiction, use of medications that affect cognitive functions, and traumatic brain injury
Key Trial Info
Start Date :
October 1 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
April 30 2025
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT06595511
Start Date
October 1 2022
End Date
April 30 2025
Last Update
September 19 2024
Active Locations (1)
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1
Istanbul Medipol University
Istanbul, Beykoz, Turkey (Türkiye), 34810