Status:
COMPLETED
Risk Factors for Beta-lactam Target Non Attainment in Critically Ill Patients BETALACTACRIT
Lead Sponsor:
Centre Hospitalier de Saint-Brieuc
Conditions:
Sepsis
Eligibility:
All Genders
18+ years
Brief Summary
Beta-lactams agents are time-dependent antibiotics. Their bactericidal effects are associated with the time spent above the minimal inhibitory concentration (MIC) of the bacteria. In ICU patients, man...
Detailed Description
The duration of patient participation extends from the inclusion visit (D1), to discharge from intensive care; if the participant is still in intensive care at D90, the last visit with data collection...
Eligibility Criteria
Inclusion
- Participant over 18 years of age.
- Hospitalized in intensive care unit.
- Bacterial infection documented by culture.
- Treatment with beta-lactam for less than 48 hours.
- Person not objecting to participation in the study. If the particpant is unable to receive the information, it will be given to a relative and his or her non-opposition will be collected; the patient's non opposition will be sought and collected as soon as his or her condition permits.
Exclusion
- Measurement of MIC of the bacterium in question impossible.
- Patients allergic to beta-lactam antibiotics.
- Patients with an estimated hospital stay of less than 3 days.
- Participants with "complex" infectious sites: central nervous system infection, osteoarticular infection, etc.
- Patients already included in the present study on the occasion of a previous beta-lactam administration.
- Adult patients under legal protection (safeguard of justice, curatorship, guardianship), persons deprived of liberty.
Key Trial Info
Start Date :
June 12 2023
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
June 30 2025
Estimated Enrollment :
300 Patients enrolled
Trial Details
Trial ID
NCT06596096
Start Date
June 12 2023
End Date
June 30 2025
Last Update
July 9 2025
Active Locations (1)
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1
FILLATRE
Saint-Brieuc, France, 22000