Status:
RECRUITING
Effect of Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) on Plasma Insulin Levels
Lead Sponsor:
Indiana University
Conditions:
Healthy
Eligibility:
All Genders
18-70 years
Phase:
NA
Brief Summary
The purpose of this study is to find out if investigators can stimulate the vagus nerve (a nerve in the body that runs from your brain to the large intestine), and influence insulin, C-peptide, and gl...
Detailed Description
STUDY OBJECTIVES Primary: The research described in this protocol is best described as an extension of the researcher's current protocol which is designed to measure cervical compound vagal nerve act...
Eligibility Criteria
Inclusion
- Healthy Volunteers
- Aged 18-70
- Willing to have ECG electrodes placed on their neck and chest areas.
- Willing to have electrodes placed in the external ear.
- Willing to have an indwelling catheter placed to avoid multiple sticks for blood draw.
Exclusion
- Unable to provide consent.
- Diabetes diagnosis per patient report
- Having known allergies to adhesive on electrode pads or bandages
- Having gastric motility issues as determined by the PI or clinical coordinator.
- Taking any medications that may affect gastric motility or cardiac variability, i.e. alpha or beta blockers for hypertension.
- Pregnant females
- Those unwilling to have the taVNS device placed in their ear.
- Those unwilling to consent to a blood draw.
- Prisoners
Key Trial Info
Start Date :
April 16 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
May 31 2026
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT06597149
Start Date
April 16 2025
End Date
May 31 2026
Last Update
November 18 2025
Active Locations (1)
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1
Indiana University Hospital
Indianapolis, Indiana, United States, 46202