Status:

COMPLETED

Antibacterial Effect of NaOCl With Etidronic Acid in Apical Periodontitis Treatment

Lead Sponsor:

Mustafa Kemal University

Conditions:

Healthy

Eligibility:

All Genders

18-65 years

Phase:

NA

Brief Summary

Sodium hypochlorite (NaOCl), the most commonly used irrigation solution during chemomechanical preparation, plays a significant role in eliminating bacteria within root canals. Additionally, after pre...

Eligibility Criteria

Inclusion

  • The study included teeth from patients aged 18-65 years who had no systemic disease and had not undergone antibiotic therapy in the past three months. To ensure standardization, all the treatments were performed by a single clinician.
  • A minimum of 2 years since the initial root canal treatment
  • Single rooted mandibular premolar with apical periodontitis (AP) and a canal filling within 4 mm from the apex on radiographic examination
  • The absence of pain on palpation and percussion, healthy periodontal tissues, and no mobility,
  • Presence of a coronal restoration (teeth that have not retained permanent restoration over the previous root canal treatment).

Exclusion

  • Patients who have received antibiotic therapy in the last 3 months,
  • Patients with diabetes, pregnancy, immunosuppression and cardiovascular disease,
  • Absence of a coronal restoration
  • Presence of pain on palpation and percussion, mobility.

Key Trial Info

Start Date :

August 17 2020

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

January 10 2021

Estimated Enrollment :

40 Patients enrolled

Trial Details

Trial ID

NCT06597825

Start Date

August 17 2020

End Date

January 10 2021

Last Update

September 19 2024

Active Locations (1)

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Hatay Mustafa Kemal University Dentistry Faculty Department of Endodontics

Antakya, Hatay, Turkey (Türkiye), 31060