Status:
COMPLETED
Pain Control in Episodic and Chronic Migraine
Lead Sponsor:
IRCCS National Neurological Institute "C. Mondino" Foundation
Conditions:
Migraine
Eligibility:
All Genders
18-70 years
Phase:
NA
Brief Summary
The phenomenon of offset analgesia (OA) refers to a disproportionately large decrease in perceived pain following a slight reduction in the intensity of a noxious heat stimulus. This phenomenon is con...
Detailed Description
Migraine is a cyclic disorder marked by varying activity in different brain regions. It is generally believed that migraine involves a pronociceptive pain modulation pattern, likely due to impaired en...
Eligibility Criteria
Inclusion
- patients affected by episodic or chronic migraine according to the International Headache Society (IHS) Classification (3rd edition), aged 18 to 70 years
Exclusion
- any other headache diagnosis according to the IHS classification
- other acute or chronic pain conditions
- serious internal, psychiatric, or neurological systemic diseases
- pregnancy, breastfeeding, skin pathologies in the tested trigeminal nerve area (V1)
- poor sleep quality the night before testing
- alcohol consumption or intense exercise within 24 hours prior to examination
- women were not assessed during their menstrual cycle.
- Use of migraine prophylactic medication for patients with EM.
Key Trial Info
Start Date :
June 15 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 15 2024
Estimated Enrollment :
90 Patients enrolled
Trial Details
Trial ID
NCT06599905
Start Date
June 15 2021
End Date
April 15 2024
Last Update
September 19 2024
Active Locations (1)
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1
Clinical Trial Center
Pavia, Italy, 27100