Status:
RECRUITING
Health Improvements by Understanding the Determinants of Residual Risk in Coronary Artery Disease and New Targets for Prevention and Treatment
Lead Sponsor:
Fondazione Toscana Gabriele Monasterio
Collaborating Sponsors:
CNR Institute of Clinical Physiology, Pisa, Italy
IRCCS SYNLAB SDN, Naples, Italy
Conditions:
Coronary Arterial Disease (CAD)
Eligibility:
All Genders
40-75 years
Brief Summary
Current medical treatments, in patients with stable coronary artery disease (CAD), mainly target established risk factors and are able to reduce morbidity and mortality but still leave a substantial r...
Detailed Description
HURRICANE is an observational clinical study, performed in retrospective and prospective cohorts of patients with stable CAD, to assess the role of emerging cardiometabolic and vascular risk determina...
Eligibility Criteria
Inclusion
- RETROSPECTIVE STUDY
- patients with known or suspected stable CAD who underwent CCT for the registered studies "SMARTool" or "Studio di biomarcatori in vivo ed in vitro"
- fully accessible CCT image files and whole blood and plasma/serum aliquots stored in BioBank
- written informed consent
Exclusion
- overt heart failure (NYHA Class III-IV) and/or reduced systolic LV function (LVEF\<40%)
- relevant comorbid conditions limiting expected survival to less than 1 year
- CCT exam of suboptimal quality
- PROSPECTIVE STUDY
- Inclusion Criteria:
- patients with suspected stable CAD clinically referred for a first diagnostic CCT
- fully accessible CCT image files and whole blood and plasma/serum aliquots stored in BioBank
- written informed consent
Key Trial Info
Start Date :
July 7 2023
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 1 2025
Estimated Enrollment :
961 Patients enrolled
Trial Details
Trial ID
NCT06601153
Start Date
July 7 2023
End Date
December 1 2025
Last Update
September 19 2024
Active Locations (2)
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1
Fondazione Toscana Gabriele Monasterio
Pisa, Italy, Italy, 56124
2
Irccs Synlab Sdn
Napoli, Italy, 80121