Status:

COMPLETED

The Effect of I-PRF As An Adjunct to Non-Surgical Periodontal Therapy on Clinical Parameters in Smokers With Periodontitis

Lead Sponsor:

Abant Izzet Baysal University

Conditions:

Periodontitis

Eligibility:

All Genders

20-65 years

Phase:

NA

Brief Summary

The aim of this clinical trial is to evaluate the effect of subgingival injectable platelet-rich fibrin (i-PRF) application on clinical periodontal parameters as an adjunct to non-surgical periodontal...

Detailed Description

Twenty-five systemically healthy, smoker patients with periodontitis were included in the study. All individuals were examined at baseline, 1st and 3rd months after non-surgical periodontal treatment ...

Eligibility Criteria

Inclusion

  • patients were systemically healthy adults,
  • having at least 20 natural teeth,
  • the presence of contralateral periodontal pockets (PPD≥ 5 mm) and CAL≥2 mm on a minimum of two premolar/molar teeth on each side and no furcation involvement,
  • smoking more than 10 cigarettes per day for at least 5 years,
  • stage II-III periodontitis patients

Exclusion

  • individuals had past periodontal treatment within 6 months
  • individuals had used systemic antibiotics in the last 6 months or anti- inflammatory drugs in the last 3 months before the beginning of the trial,
  • patient with clotting and hematologic disorders, had used drugs affecting the natural coagulation process,
  • patients taking medications that affect the gingival and periodontal tissues
  • pregnant or breastfeeding females

Key Trial Info

Start Date :

September 4 2023

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

April 30 2024

Estimated Enrollment :

25 Patients enrolled

Trial Details

Trial ID

NCT06605547

Start Date

September 4 2023

End Date

April 30 2024

Last Update

September 23 2024

Active Locations (1)

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Bolu Abant Izzet Baysal University

Bolu, Turkey (Türkiye), 14030