Status:

ACTIVE_NOT_RECRUITING

Assessment of Taurine Concentration in Older Women With/Without Obesity And With/Without Type 2 Diabetes Mellitus

Lead Sponsor:

University of Sao Paulo

Collaborating Sponsors:

Fundação de Amparo à Pesquisa do Estado de São Paulo

Conditions:

Obesity and Type 2 Diabetes

Eligibility:

FEMALE

60-75 years

Brief Summary

Aging is a multifactorial process marked by several epigenetic and molecular changes, such as telomere shortening, DNA exposure to damage, mitochondrial dysfunction, accumulation of senescent cells, a...

Detailed Description

The aim of this study is to investigate whether health status (women with obesity, T2DM and no comorbidities) promotes changes in plasma taurine concentration and to correlate this concentration with ...

Eligibility Criteria

Inclusion

  • Have not exercised regularly for at least 3 months;

Exclusion

  • use of insulin;
  • consumption of multivitamin supplements or antioxidant vitamins;
  • consumption of mineral supplements such as Copper, Zinc and/or Manganese;
  • liver disease;
  • chronic kidney disease;
  • coronary disease;
  • thyroid disorders;
  • infectious diseases;
  • regular consumption of alcoholic beverages;
  • smoking;
  • the Mini Mental State Examination (MMSE) will be applied, which has a total score ranging from 0-30 points. For the elderly women to be included in the study, they must have a score greater than or equal to 13 points

Key Trial Info

Start Date :

February 28 2024

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

January 30 2026

Estimated Enrollment :

40 Patients enrolled

Trial Details

Trial ID

NCT06607068

Start Date

February 28 2024

End Date

January 30 2026

Last Update

September 23 2024

Active Locations (1)

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Escola de Educação Física e Esporte de Ribeirão Preto

Ribeirão Preto, São Paulo, Brazil, 14040900