Status:
NOT_YET_RECRUITING
Thermal Ablation Vs Thyroidectomy for Large Benign Thyroid Nodules
Lead Sponsor:
Ming-an Yu
Conditions:
Benign Thyroid Nodules
Eligibility:
All Genders
18-80 years
Brief Summary
To compare the safety, efficacy and quality of life between staged thermal ablation and thyroidectomy in the treatment of Large benign thyroid nodules.
Detailed Description
Large benign thyroid nodules （BTNs）usually cause compressive symptoms or cosmetic concerns and therefore require treatment. Thyroidectomy remains the mainstay treatment for large, symptomatic BTNs. Ho...
Eligibility Criteria
Inclusion
- benign thyroid nodules confirmed by surgical pathology in surgery group, and by two separate US-guided fine-needle aspiration (FNA) or core needle biopsy (CNB) in thermal ablation group;
- the largest diameter of the nodule ≥4 cm;
- the presence of nodule-related symptoms, cosmetic concerns, or psychological stress;
- patients treated with surgery, or staged thermal ablation (who explicitly refused surgery);
- more than 12-month follow-up duration
Exclusion
- suspicion of malignant nodule on ultrasound findings (e.g., marked hypoechoic, microcalcifications, or ill-defined margins);
- comorbidities of other severe diseases;
- without complete treatment and/or follow-up information
Key Trial Info
Start Date :
September 10 2024
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 1 2027
Estimated Enrollment :
300 Patients enrolled
Trial Details
Trial ID
NCT06607133
Start Date
September 10 2024
End Date
December 1 2027
Last Update
September 23 2024
Active Locations (1)
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1
China-Japan Friendship Hospital
Beijing, Beijing Municipality, China, 100029