Status:
RECRUITING
Timing and Facilitation Effects of Theta-Burst Stimulation in the Reading and Language Networks
Lead Sponsor:
Georgia State University
Conditions:
Reading
Language
Eligibility:
All Genders
18-30 years
Phase:
NA
Brief Summary
The purpose of this study is to understand how transcranial magnetic stimulation affects how quickly, easily, and accurately a person read. Transcranial magnetic stimulation is a technique that uses m...
Eligibility Criteria
Inclusion
- Inclusion Criteria:
- Subjects must have a minimum of low average intellectual functioning (\>=80) on at least one subscale on the Wechsler Abbreviated Scale of Intelligence-2 (WASI-2; Wechsler, 2011) to be included.
- Within a normal range of reading skills as \>85 on the Test of Word Reading Efficiency - Second Edition (TOWRE-2; Torgesen et al., 2012) and the Woodcock-Johnson IV Tests of Achievement (WJ-IV; Schrank et al., 2014)
- Individuals with a documented history of learning disability will not be included. This will be determined via demographics questionnaire.
- Subjects must be between the ages of 18 and 30 to be included. This will be determined via demographics questionnaire.
- Because reading is critically linked to language, only individuals who are native speakers of English will be included in the study. This will be determined via demographics questionnaire.
- The reading network is typically localized to the left side of the brain. However, left-handed individuals may have different brain lateralization, introducing an important confound to the study. Therefore, only right-handed individuals will be included in the study. This will be determined via demographics questionnaire.
- Individuals who have hearing deficits (\>25dB at 500+ Hz), visual deficits (\>20/40), serious emotional problems, certain neurological conditions (e.g., uncontrolled seizure disorders) will not be included. This will be determined via CABI Screening Forms and Demographics Questionnaire.
- Individuals with certain metals in their bodies or with certain health conditions will not be included. If an individual has braces on their teeth, a cardiac pacemaker; hearing aid; other metal in their body or eyes (which may include certain metallic-embedded tattoos), including but not limited to pins, screws, shrapnel, plates, dentures or other metal objects they will not be included. This will be determined via CABI Screening forms.
- Individuals with MRI Screening and Contraindication Forms which do not pass MRI Tech review will not be included.
- Individuals with TMS Screening Forms which do not pass TMS Tech review will not be included.
Exclusion
Key Trial Info
Start Date :
May 1 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2028
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT06608680
Start Date
May 1 2023
End Date
December 31 2028
Last Update
September 23 2024
Active Locations (1)
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1
Georgia State University
Atlanta, Georgia, United States, 30303