Status:
NOT_YET_RECRUITING
Sensitivity and Specificity of Leucocytes Subpopulation Versus Platelet Indices in Prediction of Clinical Outcome for Candidates With Sepsis. A Bi-centric Observational Clinical Trial
Lead Sponsor:
Minia University
Conditions:
Sepsis
Eligibility:
All Genders
20-70 years
Brief Summary
Leucocyte subpopulation and platelet indices analysis can predict clinical outcome
Eligibility Criteria
Inclusion
- Adult population of both sex, aged 20 or older admitted to the ICU with a diagnosis of sepsis were screened for inclusion within 48 h of presentation to the hospital. Sepsis was defined as per the Sepsis-3 definition, 6 ie, the presence of suspected or documented infection with organ dysfunction determined by an acute increase of sequential organ failure assessment (SOFA) score by 2 or more points
Exclusion
- Patient refusal.
- History of surgery in the last 7 days from admission.
- Immunocompromised population ( post-transplantation, steroid use \> 5 mg per day, malignancy, HIV, on chemotherapy).
- Population with history of thrombocytopenia ( ITP, aplastic anemia, drug induced)
- History of thrombocytosis ( idiopathic thrombocytosis, post-splenectomy)
- History of platelet transfusion one week before admission.
- Bone marrow transplanted population .
- Chronic liver and kidney disease.
- Von-Willebrand disease.
- Patients on antiplatelet therapy ( Aspirin, clopidogrel).
- Thrombocytopenic population ( ITP, TTP,HELLP) .
- Myelodysplastic or proliferative patients.
- Blood dyscarsiasis
- Obestetric parturients.
Key Trial Info
Start Date :
September 25 2024
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
August 20 2025
Estimated Enrollment :
161 Patients enrolled
Trial Details
Trial ID
NCT06612307
Start Date
September 25 2024
End Date
August 20 2025
Last Update
September 25 2024
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