Status:

COMPLETED

The Effect of Probiotics on the Improvement of Intestinal and Immune Function

Lead Sponsor:

Wecare Probiotics Co., Ltd.

Conditions:

Intestinal and Immune Function Improved

Eligibility:

All Genders

18-45 years

Phase:

NA

Brief Summary

Evaluate the effectiveness and safety of Lactobacillus delbrueckii subsp. bulgaricus LB42 as a food supplement compared to a placebo in improving intestinal and immune functions in healthy adults.

Eligibility Criteria

Inclusion

  • Age 18-45 years
  • Willing to undergo 3 follow-up visits during the intervention period
  • Willing to provide 2 blood, urine, and stool samples during the intervention period
  • Willing to self-administer one of the probiotics/placebo once daily during the intervention period
  • Good eyesight, able to read and write, and can wear glasses
  • Have good hearing and be able to hear and understand all instructions during the intervention

Exclusion

  • Suffering from digestive disorders, mainly gastrointestinal disorders (celiac disease, ulcerative colitis, Crohn's disease)
  • Has a severe neurological condition (epilepsy, stroke, severe head trauma, meningitis within the past 10 years, brain surgery, brain tumor, prolonged coma - excluding general anesthesia)
  • Has received/is receiving treatment for the following psychiatric disorders: alcohol/drug/substance abuse dependence, schizophrenia, psychosis, bipolar disorder
  • Take medication for depression or low mood
  • Suffering from internal organ failure (heart, liver, or kidney failure, etc.)
  • Radiotherapy or chemotherapy in the past
  • Surgery/procedure under general anesthesia within the past three years, or planned to undergo a procedure/procedure under general anesthesia within the next 3 months during this trial
  • Have had hepatitis (hepatitis B, hepatitis C), HIV or syphilis in the past

Key Trial Info

Start Date :

March 1 2025

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 15 2025

Estimated Enrollment :

52 Patients enrolled

Trial Details

Trial ID

NCT06873438

Start Date

March 1 2025

End Date

August 15 2025

Last Update

October 3 2025

Active Locations (1)

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1

Xu fei

Zhengzhou, Henan, China, 210095