Status:

RECRUITING

The Impact of Endoscopic Endonasal Skull Base Surgery on Olfaction

Lead Sponsor:

Universitaire Ziekenhuizen KU Leuven

Conditions:

Meningioma

Pituitary Disease

Eligibility:

All Genders

18-70 years

Brief Summary

In this study, the research team will investigate the incidence and etiology of olfactory dysfunction following endoscopic endonasal skull base surgery, by combining clinical assessments with histomol...

Detailed Description

The incidence of olfactory dysfunction following endoscopic endonasal skull base surgery remains unclear in current research, and the results vary widely. Additionally, the pathophysiology of this pos...

Eligibility Criteria

Inclusion

  • Adult patients scheduled for endoscopic endonasal skull base surgery

Exclusion

  • Pre-existing anosmia
  • Patients has a history of previous endoscopic endonasal skull base surgery

Key Trial Info

Start Date :

March 18 2025

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

September 1 2029

Estimated Enrollment :

154 Patients enrolled

Trial Details

Trial ID

NCT06874426

Start Date

March 18 2025

End Date

September 1 2029

Last Update

April 23 2025

Active Locations (3)

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Page 1 of 1 (3 locations)

1

KU Leuven

Leuven, Vlaams-Brabant, Belgium, 3000

2

Max Planck Research Unit for Neurogenetics

Frankfurt am Main, Hesse, Germany, 69

3

Leiden University Medical Center

Leiden, South Holland, Netherlands, 10702