Status:
COMPLETED
Retrospective Cohort Study on the Impact of PDL Treatment History on the Efficacy of HMME-PDT in Treating PWS Children
Lead Sponsor:
Second Affiliated Hospital of Xi'an Jiaotong University
Conditions:
Port-Wine Stain
Eligibility:
All Genders
1-3 years
Brief Summary
This retrospective study investigated the influence of prior pulse dye laser (PDL) treatment on the effectiveness of Hemoporfin-PDT in young children aged 1-3 years with PWS. The study population inc...
Detailed Description
Background Hemoporfin-mediated photodynamic therapy (Hemoporfin-PDT) is considered a safe and effective treatment for port-wine stains (PWS). This study aims to investigate the influence of prior puls...
Eligibility Criteria
Inclusion
- Patients clinically diagnosed with PWS (Port Wine Stain) who were between 1 and 3 years old at the time of their first HMME-PDT treatment.
- Patients who, after evaluation by a clinician, are deemed eligible for HMME-PDT treatment and whose guardians have signed an informed consent form.
- Patients who have undergone two or more HMME-PDT treatments.
- ④ Patients with complete basic information and treatment-related information.
Exclusion
- Exclusion of patients with syndromes associated with PWS.
- Exclusion of patients with a history of treatments for PWS other than PDL treatment.
- Patients with other vascular malformations. ④ Exclusion of patients who have received any other PWS treatment within 2 months prior to HMME-PDT treatment.
Key Trial Info
Start Date :
April 1 2024
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
September 1 2024
Estimated Enrollment :
273 Patients enrolled
Trial Details
Trial ID
NCT06875492
Start Date
April 1 2024
End Date
September 1 2024
Last Update
March 13 2025
Active Locations (1)
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1
The Second Affiliated Hospital of Xi'an Jiaotong University
Xi'an, Shaanxi, China, 710004