Status:

RECRUITING

Beliefs, Attitudes, and Response to Genetic Testing in SarcomaPatients

Lead Sponsor:

University of Utah

Collaborating Sponsors:

National Cancer Institute (NCI)

University of New South Wales

Conditions:

Leiomyosarcoma

Eligibility:

All Genders

18+ years

Brief Summary

Genomic research has shown that a portion of leiomyosarcomas can be attributed to an underlying cancer predisposition syndrome. However, the optimal approach for incorporating germline testing into th...

Detailed Description

This is a descriptive study to explore attitudes to genomics and return of genetic information and examine the cognitive and affective impact of receiving germline genetic information among LMS patien...

Eligibility Criteria

Inclusion

  • Inclusion LMS Proband
  • Actionable germline PV detected in the research context
  • Living
  • No prior germline testing for this PV
  • Able to speak and read English
  • Mentally competent
  • Age 18 or older
  • Relative of LMS Proband
  • 25-50% chance for having inherited the PV
  • No prior germline testing for this PV
  • Able to speak and read English
  • Mentally competent
  • Age 18 or older
  • Exclusion (both cohorts)
  • \<18 years
  • Unable to read or write

Exclusion

    Key Trial Info

    Start Date :

    July 9 2024

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ESTIMATED

    End Date :

    August 1 2027

    Estimated Enrollment :

    300 Patients enrolled

    Trial Details

    Trial ID

    NCT06875700

    Start Date

    July 9 2024

    End Date

    August 1 2027

    Last Update

    June 13 2025

    Active Locations (1)

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    Huntsman Cancer Institute at the University of Utah

    Salt Lake City, Utah, United States, 84112