Status:
RECRUITING
Improving Cognitive Recovery in Multiple Sclerosis
Lead Sponsor:
King's College London
Collaborating Sponsors:
King's College Hospital NHS Trust
Conditions:
Multiple Sclerosis
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
This study aims to find out whether an adapted version of an existing cognitive rehabilitation program, CIRCuiTS (https://www.circuitstherapyinfo.com), can be used to improve everyday thinking skills ...
Detailed Description
Objectives The primary goal of this study is to assess the practical aspects of the research to determine whether a larger, fully-scale trial will be viable and acceptable. A feasibility decision wil...
Eligibility Criteria
Inclusion
- Participants must have a confirmed diagnosis of Multiple Sclerosis (MS), as verified by a healthcare provider.
- Participants should be in a relatively stable phase of their condition, not experiencing a severe relapse or acute health crisis at the time of the study.
- Participants must have sufficient cognitive abilities to engage in therapy sessions, meaning they can follow instructions and perform the cognitive tasks required during the remediation program.
- Participants must be able to effectively communicate in English, both verbally and in writing, to interact with therapists and complete assessments.
- Participants must be adults aged 18 years or older.
- Participants should have personal experience with cognitive challenges related to MS, such as problems with memory, attention, or problem-solving.
- Participants must be willing and able to commit to attending all therapy sessions over the 12-week period, as well as attending assessments and completing any required homework or independent sessions.
- Participants must provide informed consent, demonstrating that they understand the purpose of the therapy trial and are willing to engage in the course of cognitive remediation.
- Participants must have access to a computer (laptop or desktop) for at least one hour per week during the treatment period (12 weeks).
Exclusion
- Individuals who are currently receiving cognitive remediation or a similar intervention.
- Individuals with high levels of depression, indicated by a score greater than 9 on the Patient Health Questionnaire-9 (PHQ-9).
- Individuals with active suicidal ideation, indicated by a score greater than 0 on question 9 of the PHQ-9.
- Individuals with a diagnosis of a psychotic disorder or bipolar disorder.
- Physical disabilities that severely limit the individual's ability to attend therapy sessions or engage with the cognitive tasks (whether in-person or online) may lead to exclusion if suitable adaptations cannot be made.
Key Trial Info
Start Date :
July 17 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
September 15 2026
Estimated Enrollment :
24 Patients enrolled
Trial Details
Trial ID
NCT06877273
Start Date
July 17 2025
End Date
September 15 2026
Last Update
July 22 2025
Active Locations (1)
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1
King's College London
London, East of England, United Kingdom