Status:

ACTIVE_NOT_RECRUITING

Photodynamic Treatment as Part of Oral Healthcare on Persons With Sjögren's Syndrome

Lead Sponsor:

Koite Health Oy

Collaborating Sponsors:

Metropolia University of Applied Sciences

Conditions:

Sjogren Syndrome

Xerostomia

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

This thesis study will investigate whether the regular use of antibacterial photodynamic therapy can alleviate dry mouth symptoms in patients with Sjogren's syndrome and thus be a potential addition t...

Detailed Description

Sjogren's syndrome is a chronic autoimmune disease that has a holistic impact on a patient's health. The most significant consequence in terms of oral health is the destruction of the salivary glands ...

Eligibility Criteria

Inclusion

  • Adult (minimum 18 years of age) person with Sjogren's syndrome, with dry mouth symptoms but some saliva secretion.
  • Otherwise perceived health good, primary Sjögren's syndrome patient.
  • No need for antibiotic prophylaxis at the time of a limited oral examination.
  • Signed written informed consent.
  • Subject's co-operation allows participation in the study.

Exclusion

  • Pregnancy and/or breastfeeding.
  • Fungal infection in the mouth
  • Poor oral health, such as caries lesions or advanced periodontitis.
  • Fixed dentures, or orthodontics.
  • No saliva secretion.
  • Bisphosphonate drugs, multiple (more than two) medications in use.
  • Participation in other oral health research at the same time.

Key Trial Info

Start Date :

May 24 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2025

Estimated Enrollment :

16 Patients enrolled

Trial Details

Trial ID

NCT06877546

Start Date

May 24 2025

End Date

December 1 2025

Last Update

August 8 2025

Active Locations (1)

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Metropolia University of applied sciences

Helsinki, Finland