Status:
RECRUITING
DuoCor Ventricular Assist System Early Feasibility Study
Lead Sponsor:
Shenzhen Core Medical Technology CO.,LTD.
Conditions:
Heart Failure
Eligibility:
All Genders
18-75 years
Phase:
NA
Brief Summary
Feasibility study of the DuoCor Ventricular Assist System as a treatment for advanced total heart failure patients.
Eligibility Criteria
Inclusion
- Requiring a biventricular mechanical circulatory support, defined by either of the following criteria:
- Persistent total heart failure despite under optimal medical management based on current heart failure practice guidelines. OR
- Development of refractory right heart failure following left ventricular assist device (LVAD) implantation, unresponsive to pharmacological interventions for right heart failure.
- Patient has signed the informed consent, has full understanding of procedures, and is committed to following study requirements.
Exclusion
- Intolerance to anticoagulant or antiplatelet therapies or any other peri/post-operative therapy the investigator will require based upon the patient's health status.
- Technical obstacles which pose the implantation as unsuitable, obtaining the body type, body surface area, and anatomical conditions related to the planned implantation site, in the judgment of the experienced investigators.
- Pregnancy.
- Age \> 75 years.
- Presence of an active, uncontrolled infection.
- Brain death.
- History of confirmed, untreated abdominal aortic aneurysm (AAA) or thoracic aortic aneurysm (TAA) \> 5 cm in diameter.
- Irreversible cognitive dysfunction, psychosocial issues, or psychiatric disease, likely to impair compliance with the study protocol and DuoCor VAS management which, in the opinion of the investigator, could interfere with the ability to manage the therapy.
Key Trial Info
Start Date :
July 4 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
October 1 2026
Estimated Enrollment :
10 Patients enrolled
Trial Details
Trial ID
NCT06878508
Start Date
July 4 2024
End Date
October 1 2026
Last Update
March 17 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Wuhan, Hubei, China, 430022