Status:

NOT_YET_RECRUITING

Radiographic and Histomorphometric Assessment for Alveolar Ridge Preservation Using Autogenous Tooth Graft From Extracted Tooth Combined With Simvastatin 1:1 Versus Autogenous Tooth Graft

Lead Sponsor:

Cairo University

Conditions:

Alveolar Ridge Preservation

Horizontal Alveolar Bone Loss

Eligibility:

All Genders

20-45 years

Phase:

NA

Brief Summary

This study will be held to overcome the previous limitations related to bone loss after teeth extraction by taking advantages from both Autogenous tooth graft and Simvastatin which will offer a promis...

Detailed Description

Alveolar ridge resorption following tooth extraction is one of the greatest challenges in dentistry, especially for patients seeking dental implants. The alveolar ridge undergoes significant decrease ...

Eligibility Criteria

Inclusion

  • Patients with badly broken, non-restorable, or periodontally hopeless non molar single rooted teeth.
  • Age from 20-45 years old(6,13). No sex predilection.
  • Medically free from any medical condition that would interfere with bone healing.
  • Patients with status classification (ASA I \& II) with adequate oral hygiene condition.
  • Alveolar sockets free from any preexisting periapical pathology based on intraoral periapical or panoramic radiograph.

Exclusion

  • Patients with any medical condition that contraindicated the procedure and general contraindications for Implant Surgery(6,13)
  • Patients who are allergic to Simvastatin drug.(6)
  • Presence of active infection around the tooth or remaining root.
  • Psychological reasons that might affect the procedure or the subsequent follow up visits.
  • Heavy smokers
  • Immunosuppressed or Immunocompromised.(13)

Key Trial Info

Start Date :

June 10 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

June 10 2026

Estimated Enrollment :

26 Patients enrolled

Trial Details

Trial ID

NCT06879171

Start Date

June 10 2025

End Date

June 10 2026

Last Update

May 20 2025

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