Status:
COMPLETED
Comparison of Single-Dose Tranexamic Acid Vs. Placebo in Ovarian Cancer Surgery
Lead Sponsor:
Sheikh Zayed Medical College
Conditions:
Ovarian Cancer
Perioperative Blood Loss
Eligibility:
FEMALE
18-60 years
Phase:
NA
Brief Summary
This study evaluated the effectiveness of a single dose of tranexamic acid compared to a placebo in reducing blood loss and the need for blood transfusions in women undergoing surgery for ovarian canc...
Detailed Description
After obtaining approval from the ethical committee and CPSP and securing informed consent from the participants, all females who met the inclusion criteria were enrolled in the study from the outpati...
Eligibility Criteria
Inclusion
- Age 18-60.
- Female gender.
- Ovarian cancer of \> 12 months duration.
- FIGO stage I-III.
- American Society of Anesthesiologists (ASA) status 1-3.
Exclusion
- Ovarian cancer of FIGO stage IV
- ASA status 4-6.
- Hypersensitivity to tranexamic acid, (assessed by reviewing previous medical record).
- History of bleeding or clotting disorders (assessed by reviewing previous medical record).
- Impaired renal function (serum creatinine \> 1.3 mg/dl).
- History of coronary heart disease (assessed by reviewing previous medical record).
Key Trial Info
Start Date :
July 12 2023
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 12 2024
Estimated Enrollment :
372 Patients enrolled
Trial Details
Trial ID
NCT06879353
Start Date
July 12 2023
End Date
July 12 2024
Last Update
March 19 2025
Active Locations (1)
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1
Sheikh Zayed Medical college/hospital
Rahim Yar Khan, Punjab Province, Pakistan, 66000