Status:
RECRUITING
The Effect of Dairy Intake on Body Weight and Composition and Metabolic Health in Adolescents and Seniors
Lead Sponsor:
University of Toronto
Conditions:
Dairy Consumption
Metabolic Health
Eligibility:
All Genders
14-75 years
Phase:
NA
Brief Summary
The goal of this study is to examine how regular dairy intake affects body weight, body composition, and metabolic health in overweight and prediabetic adolescents (ages 14-17) and older adults (ages ...
Eligibility Criteria
Inclusion
- Age 14-17 years old (adolescents) or 60-75 years old (seniors)
- BMI z-score \>+1SD, \<+2SD (adolescents) or BMI 25-30 kg/m2 (seniors)
- Waist circumference \> 88 cm for women and \> 102 cm for men (seniors)
- FBG 5.6-6.9 mmol/L (prediabetes)
- Consumes ≤1 serving of dairy per day
- Willing to maintain habitual diet, physical activity, and body weight throughout the study.
- Willing to maintain current dietary supplement use throughout the study. On the first day, the participants agree not to take any dietary supplements until the completion of the study.
- Willing to abstain from alcohol consumption for 24 hours prior to all test visits.
- Willing to avoid vigorous physical activity for 24 hours prior to all test visits.
- Understands the study procedures and is willing to provide informed consent by parent/guardian and assent by participant to participate in the study and authorization to release relevant protected health information to the study investigator.
Exclusion
- Fasting BG ≥ 7mmol/L
- Blood pressure systolic ≥ 130mmHg or diastolic ≥ 80mmHg (adolescents) or systolic ≥ 160 mmHg or diastolic pressure ≥ 100 mmHg
- Smoking (tobacco and/or cannabis product use in the last 6 months)
- Thyroid problems
- History of CVDs, diabetes, liver or kidney disease, inflammatory bowel disease, celiac disease, short bowel syndrome, any malabsorption syndrome, pancreatitis, gallbladder, or biliary disease.
- Presence of gastrointestinal disorder or surgeries within the past year.
- Use of the prescription or non-prescription drugs, herbal or nutritional supplements known to affect the outcome of the study as per the investigator's judgment (including prebiotics and probiotics).
- History of childhood obesity
- Known to be pregnant, lactating, or not postmenopausal for at least a year and/or is taking hormonal treatments
- Unwillingness or inability to comply with the experimental procedures
- Known intolerance, sensitivity, or allergy to dairy, gluten, or any other study treatments.
- Consumption of protein powders/supplements
- Extreme dietary habits (e.g., Atkins diet, very high-protein diets, etc.)
- Weight gain or loss of \>10 lbs. in the previous three months.
- Excessive alcohol intake (more than 2 drinks per day or 9 per week)
- Restrained eating, identified by a score of ≥11 on the Eating Habits Questionnaire
Key Trial Info
Start Date :
October 1 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 1 2028
Estimated Enrollment :
240 Patients enrolled
Trial Details
Trial ID
NCT06879652
Start Date
October 1 2025
End Date
June 1 2028
Last Update
October 6 2025
Active Locations (2)
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1
Department of Nutritional Sciences
Toronto, Ontario, Canada, M5S 1A8
2
Nutrition Intervention Center
Toronto, Canada, M5S 3H2