Status:
ACTIVE_NOT_RECRUITING
The Locus Coeruleus, Norepinephrine and Cognitive Aging
Lead Sponsor:
Cornell University
Conditions:
Alzheimer Disease
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The locus coeruleus (LC) has recently been identified as one of the earliest sites of damage in AD with pathological lesions appearing as early as the mid-20s. In this study, the investigators use a v...
Detailed Description
Unfortunately, most people are personally familiar with the devastating consequences of neurodegenerative disorders such as Alzheimer's disease (AD) and Parkinson's disease (PD). The number of older a...
Eligibility Criteria
Inclusion
- 18+ years of age
- Able to speak and understand English
- Hearing and vision correctable to normal or near-normal
- Willing and able to use a touchscreen
- Willing and able to use a keyboard and mouse
- Willing and able to undergo a MRI scan at the Cornell MRI Facility lasting approximately 90 minutes.
Exclusion
- Moderate or severe brain injury
- Serious neurological disorders such as epilepsy
- Recent concussion
- Colorblindness
- Use of street drugs
- Cardiac arrhythmias
Key Trial Info
Start Date :
June 1 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
January 1 2026
Estimated Enrollment :
150 Patients enrolled
Trial Details
Trial ID
NCT06880510
Start Date
June 1 2025
End Date
January 1 2026
Last Update
September 30 2025
Active Locations (1)
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1
Cornell University
Ithaca, New York, United States, 14850