Status:
COMPLETED
Minimally Invasive Surgical Intervention for Hirschsprung Disease
Lead Sponsor:
National Children's Hospital, Vietnam
Conditions:
Hirschsprung Disease
Eligibility:
All Genders
Up to 18 years
Phase:
NA
Brief Summary
Hirschsprung's disease (HD) is one of the most common congenital conditions, with a global incidence of 1/5000 newborns; the prevalence in the Vietnamese population is even higher. The absence of ente...
Detailed Description
Hirschsprung's disease (HD) is one of the most common congenital disorders affecting the gastrointestinal tract, with a global incidence of approximately 1 in 5,000 live births. However, studies sugge...
Eligibility Criteria
Inclusion
- Age: From 1 to 28 days old
- Diagnosis: Hirschsprung disease was diagnosed based on clinical presentation, intraoperative frozen section biopsy, and postoperative histopathological findings showing absence of ganglion cells.
- Surgical Approach: Patients underwent SILEP through a single periumbilical incision, with no additional abdominal incisions. All surgeries were conducted by the same team, and postoperative care was provided according to a standardized protocol.
- Parents or guardians provided consent to participate in the study and committed to following the scheduled follow-up visits.
Exclusion
- Patients exhibiting severe HAEC, bowel obstruction, or peritonitis at the time of operation
- Those with a history of failed Hirschsprung disease surgery, prior abdominal operations, or colostomy
- Individuals with contraindications to laparoscopic procedures, such as bleeding disorders or significant congenital heart defects
- Cases where parents or legal guardians refused consent for study participation
Key Trial Info
Start Date :
January 1 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 1 2025
Estimated Enrollment :
23 Patients enrolled
Trial Details
Trial ID
NCT06880666
Start Date
January 1 2020
End Date
March 1 2025
Last Update
June 15 2025
Active Locations (1)
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1
Department of Surgery, The National Children Hospital
Hanoi, Vietnam