Status:

RECRUITING

A Prospective Multicenter Registry Study on BASIS Technique for Endovascular Therapy of Acute Large Vessel Occlusion Strokes Due to Intracranial Atherosclerotic Disease

Lead Sponsor:

Fujian Medical University Union Hospital

Collaborating Sponsors:

Zhangzhou Municipal Hospital of Fujian Province

First Affiliated Hospital of Jinan University

Conditions:

Acute Ischemic Stroke

ICAS - Intracranial Atherosclerosis

Eligibility:

All Genders

18+ years

Brief Summary

This study will explore the safety and efficacy of BASIS technology in ICAS-LVO lesions through a multicenter, prospective, registry, observational single-arm study.By registering intraoperative recan...

Detailed Description

This project intends to set up a prospective multi-center single-arm study with no control group and no upper limit of cases. Using BASIS (Balloon AngioplaSty with the dIstal protection of Stent retr...

Eligibility Criteria

Inclusion

  • Age ≥18 years old;
  • Ischemic stroke;
  • Within 72 hours from the onset of symptoms to the time of visit, including post-awakening stroke or blindness For stroke patients, the time when symptoms start is defined as "the last normal time";
  • Neuroimaging examination indicated occlusion of anterior or posterior intracranial large vessels, TOAST type was large atherosclerosis type.
  • BASIS technique was used for intravascular therapy.

Exclusion

  • Neuroimaging findings on admission, acute occlusion of multiple vessels and tandem lesions;
  • History of atrial fibrillation or heart valve surgery;
  • There are clinical contraindications to the use of antiplatelet drugs (hemophilia or thrombocytopenia).Rare disease, known history of coagulation disorders, platelet abnormalities; There is active internal bleeding, intracranial Bleeding history, arteriovenous malformation, aneurysm, etc.);
  • Other types of stroke, including hemorrhagic stroke.

Key Trial Info

Start Date :

January 1 2024

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 31 2025

Estimated Enrollment :

250 Patients enrolled

Trial Details

Trial ID

NCT06881420

Start Date

January 1 2024

End Date

December 31 2025

Last Update

March 18 2025

Active Locations (1)

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Fujian Medical University Union Hospital

Fuzhou, Fujian, China

A Prospective Multicenter Registry Study on BASIS Technique for Endovascular Therapy of Acute Large Vessel Occlusion Strokes Due to Intracranial Atherosclerotic Disease | DecenTrialz