Status:

NOT_YET_RECRUITING

Low-Dose Amoxicillin Dual-Therapy Combined with Licorice and Lotus Root Powder Helicobacter Pylori Treatment

Lead Sponsor:

Second Affiliated Hospital, School of Medicine, Zhejiang University

Conditions:

HELICOBACTER PYLORI INFECTIONS

Eligibility:

All Genders

18-70 years

Phase:

NA

Brief Summary

In recent years, the increasing prevalence of Helicobacter pylori (H. pylori, Hp) resistance has led to a gradual decline in the eradication rate of Hp. The growing resistance to antibiotics, particul...

Detailed Description

Helicobacter pylori (H. pylori, Hp) is closely associated with chronic gastritis, peptic ulcers, gastric cancer and is classified as a Group I carcinogen. In recent years, the increasing prevalence of...

Eligibility Criteria

Inclusion

  • Age 18-70 years, regardless of sex; Positive for Helicobacter pylori (Hp); No use of proton pump inhibitors (PPIs), H2-receptor antagonists, antibiotics, or bismuth compounds within the past 4 weeks;

Exclusion

  • A history of gastric or duodenal surgery; Presence of other severe comorbidities, including significant cardiac, hepatic, or renal dysfunction, malignancies, or other serious medical conditions; Allergy to any component of the investigational drug; Pregnant or breastfeeding women; Participation in another drug study within 3 months prior to enrollment in this study; Inability of the patient to accurately describe their symptoms or to comply with the requirements of this study.

Key Trial Info

Start Date :

April 1 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

August 1 2025

Estimated Enrollment :

374 Patients enrolled

Trial Details

Trial ID

NCT06881524

Start Date

April 1 2025

End Date

August 1 2025

Last Update

March 18 2025

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