Status:
RECRUITING
Functional Capacity in Anderson-Fabry Disease Patients
Lead Sponsor:
IRCCS Policlinico S. Donato
Conditions:
Anderson-Fabry Disease
Eligibility:
All Genders
Brief Summary
The goal of this observational study is to observe the relation between excercise parameters - assessed by CPET - and rest/stress hemodynamic parameters - assessed by echocardiogram and CMR - in patie...
Eligibility Criteria
Inclusion
- Patients with a genetic diagnosis of AFD, according to current guidelines;
- Informed written consent with the understanding that consent may be withdrawn by the patient at any time without prejudice to future medical care (for patients age \<18 years old, written consent from a caregiver is mandatory).
Exclusion
- eGFR \<30 ml/min and other contraindications for CMR (relative controindication: patients with implantable device);
- Musculoskeletal limitation for exercise test on the cyclo ergometer;
- Pregnant or breastfeeding women;
- Any serious medical or psychiatric illness that could, in the investigator's opinion, potentially interfere with a full comprehension of the written consent form.
Key Trial Info
Start Date :
November 13 2024
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
January 1 2032
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT06884358
Start Date
November 13 2024
End Date
January 1 2032
Last Update
March 19 2025
Active Locations (5)
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1
Spedali Civili Hospital
Brescia, Brescia, Italy, 25123
2
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
Milan, Milan, Italy, 20122
3
IRCCS Policlinico San Donato
San Donato Milanese, Milan, Italy, 20097
4
Fondazione IRCCS San Gerardo dei Tintori
Monza, Monza, Italy, 20900