Status:
RECRUITING
Dietary Intervention to Improve Fertility in Women With Endometriosis Undergoing IVF
Lead Sponsor:
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Collaborating Sponsors:
UNIVERSITE CATHOLIQUE DE LOUVAIN
Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Conditions:
Endometriosis
Eligibility:
FEMALE
18-39 years
Phase:
NA
Brief Summary
The goal of this randomized controlled trial is to assess whether a 12-week anti-inflammatory diet can improve fertility outcomes in women with endometriosis undergoing In Vitro Fertilization (IVF). ...
Detailed Description
Women who agree to participate in the study will be randomized into two groups: one group will receive standard IVF protocols, and the other will undergo a 12-week anti-inflammatory diet followed by t...
Eligibility Criteria
Inclusion
- Age \< 40 years
- Pregnancy seeking for more than 12 months
- Regular menstrual cycle, i.e. mean cycle interval between 21 and 35 days
- Ultrasonographic diagnosis of ovarian endometriomas or deep peritoneal endometriosis.
- Antral Follicle Counts (AFC) ≥ 5 (no other cause of reduced ovarian reserve).
- Absence of ureteral stenosis or intestinal subocclusive symptoms
Exclusion
- Contraindication to pregnancy
- Hydrosalpinx
- Endometriomas with a mean diameter \> 4 cm
- Submucosal fibroids or large intramural or subserosal fibroids (≥ 5 cm).
- Doubtful sonographic findings that do not allow to reliably rule out malignancy.
- severe male factor (\<1 million sperm/ml)
Key Trial Info
Start Date :
March 24 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2029
Estimated Enrollment :
438 Patients enrolled
Trial Details
Trial ID
NCT06885125
Start Date
March 24 2025
End Date
December 31 2029
Last Update
March 27 2025
Active Locations (1)
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1
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
Milan, Italy, 20122