Status:

NOT_YET_RECRUITING

Effectiveness of Curcuminoids in Controlling Postoperative Pain Following Total Laparoscopic Hysterectomy

Lead Sponsor:

Erzincan Military Hospital

Conditions:

Postoperative Care

Pain Management

Eligibility:

FEMALE

20-80 years

Phase:

PHASE4

Brief Summary

Total hysterectomy is one of the most common surgical procedures in gynecology. Total laparoscopic hysterectomy (TLH) has several advantages over open surgery, such as better cosmetic outcomes, faster...

Eligibility Criteria

Inclusion

  • Laparoscopic total hysterectomy and salpingectomy, with the option of additional procedures such as oophorectomy, uterosacral ligament plications, trans obturator tape insertion, or sentinel lymphadenectomy candidates
  • They should be able to understand and sign an informed consent
  • They should be literate enough to understand the maintenance of a diary recording pain scores, QoL-15 scores, and any adverse event

Exclusion

  • Patients with any peripheral or central neuropathic pain
  • Patients used to taking over-the-counter painkiller pills
  • Patients with a history of alcohol intake/drug dependence
  • Patients with a history of psychosis
  • \*Patients with chronic inflammatory diseases who cannot be taken off nonsteroidal anti-inflammatory drugs (NSAIDs)/painkillers
  • Patients on immunosuppressive/cytotoxic/steroid therapy. \*Patients with a known allergy to duloxetine

Key Trial Info

Start Date :

March 21 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

January 15 2026

Estimated Enrollment :

126 Patients enrolled

Trial Details

Trial ID

NCT06886035

Start Date

March 21 2025

End Date

January 15 2026

Last Update

March 20 2025

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