Status:

RECRUITING

Involvement of CDA and/or dCK Metabolizing Enzymes in the Response to Azacytidine Treatment of Patients With Hematologic Malignancies

Lead Sponsor:

Assistance Publique Hopitaux De Marseille

Conditions:

Myelodysplastic Syndromes (MDS)

Leukemia Acute Myeloid - AML

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Until now, the development of personalized medicine in oncology has relied on the use of somatic biomarkers to help therapists choose the right molecule(s) to administer, based on the genetic and mole...

Eligibility Criteria

Inclusion

  • Patients over 18 years of age
  • Patients with acute myeloid leukemia
  • Patient with myelodysplastic syndrome
  • Person who has given non-opposition
  • Patient who has signed an authorization to perform a constitutional genetic analysis (in the context of care)
  • Need for effective contraception in patients of childbearing age

Exclusion

  • Failure to obtain non-opposition
  • Adults under guardianship or safeguard of justice
  • Persons deprived of their liberty
  • Patient participating in another research project
  • Pregnancy in progress

Key Trial Info

Start Date :

June 14 2021

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

June 14 2028

Estimated Enrollment :

70 Patients enrolled

Trial Details

Trial ID

NCT06886425

Start Date

June 14 2021

End Date

June 14 2028

Last Update

March 20 2025

Active Locations (1)

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1

Hôpital de la Conception

Marseille, France, 13005