Status:
NOT_YET_RECRUITING
Systemic Activation of Inflammasomes and Frailty in Older Candidates to Kidney Transplantation
Lead Sponsor:
University Hospital, Bordeaux
Conditions:
Chronic Kidney Failure
Frailty
Eligibility:
All Genders
70+ years
Phase:
NA
Brief Summary
Kidney transplantation (KT) benefit-risk ratio assessment is a challenge in a growing population of older patients with end-stage kidney disease. A pre-KT frailty phenotype has been found predictive o...
Detailed Description
Kidney transplantation (KT) benefit-risk ratio assessment is a challenge in a growing population of older patients with end-stage kidney disease. Chronic low-grade inflammation is a hallmark of biolog...
Eligibility Criteria
Inclusion
- Inclusion criteria:
- Age ≥ 70
- Patient candidate to kidney transplantation (during assessment for inscription on the waiting-list, or during waiting time after effective inscription), without absolute contraindication
- Free, informed and written consent signed by the participant and the investigator (at the latest, on the day of inclusion and before any examination required by the research).
- Person affiliated or beneficiary of a social security scheme
- Exclusion criteria:
- Inclusion in an industrial study refusing co-inclusion in our study
- Person under guardianship, assisted decision-making or under temporary guardianship
Exclusion
Key Trial Info
Start Date :
April 15 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
February 15 2027
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT06887075
Start Date
April 15 2025
End Date
February 15 2027
Last Update
March 20 2025
Active Locations (3)
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1
CHU de Bordeaux - Hôpital Pellegrin -
Bordeaux, France, France, 33076
2
CHU de Bordeaux, Hôpital Xavier Arnozan- Gérontologie Clinique
Pessac, France, France, 33600
3
CHU de Toulouse - Hôpital Rangueil
Toulouse, France, France, 31059