Status:

COMPLETED

Platelet- Rich Plasma Injection

Lead Sponsor:

Mansoura University

Conditions:

Wound Healing

Anal Fistula

Eligibility:

All Genders

18-65 years

Phase:

NA

Brief Summary

This randomized controlled study aims to investigate the effect of injection of platelet rich plasma on the postoperative outcome of perianal wound after anal fistula surgery in terms of healing time,...

Detailed Description

Fistula-in-ano is an epithelial-lined tract connecting the anal canal to the perianal skin. Most commonly, it affects people in the third to fifth decades of life. Anal fistula arise spontaneously, w...

Eligibility Criteria

Inclusion

  • Inclusion Criteria:
  • Both genders
  • Aging between 18-65 years
  • Presented by simple anal fistula (subcutaneous, intersphincteric, or low trans-sphicnteric involving less than 30% of external anal sphincter fibers)
  • Exclusion criteria:
  • Patients with associated anorectal pathology such as anal fissure, hemorrhoids, rectal prolapse, neoplasm, solitary rectal ulcer, inflammatory bowel diseases.
  • Patients on long-acting corticosteroids or immunosuppressive drugs
  • Patients having connective tissue diseases
  • Patients with complex anal fistula.

Exclusion

    Key Trial Info

    Start Date :

    July 14 2023

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ACTUAL

    End Date :

    August 5 2024

    Estimated Enrollment :

    100 Patients enrolled

    Trial Details

    Trial ID

    NCT06887166

    Start Date

    July 14 2023

    End Date

    August 5 2024

    Last Update

    March 25 2025

    Active Locations (1)

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    Mansoura University Hospital

    Al Mansurah, Dakahliya, Egypt, 35511