Status:

ENROLLING_BY_INVITATION

Posterior Nasal Nerve Neurectomy for Treatment of Intractable Allergic Rhinitis

Lead Sponsor:

Kafrelsheikh University

Conditions:

Intractable Allergic Rhinitis

Eligibility:

All Genders

16-65 years

Phase:

NA

Brief Summary

This study aims to compare the outcomes of posterior nasal nerve neurectomy in patients with resistant Allergic rhinitis by using three different methods ( surgical resection vs radiofrequency ablatio...

Eligibility Criteria

Inclusion

  • Patients aged 16 to 65 years, fit for surgery, diagnosed as moderate to severe persistent Allergic Rhinitis, as per the ARIA guidelines having 3 or more of the typical symptoms of Allergic Rhinitis including nasal discharge, repeated attacks of sneezing, nasal itching and nasal obstruction.

Exclusion

  • • Patients with Coexisting nasal pathologies that could influence the outcomes of the surgery like: chronic granulomatous diseases of the nose, nasal tumors, chronic sinsitis with or without nasal polyps, etc.
  • Patients who had used topical steroid nasal spray, oral or topical antihistamines, oral leukotriene antagonists, oral or tobical nasal decongestants in the last 2 weeks.
  • Immunocompromised patients, Systemic disease affecting prognosis such as diabetes mellitus, hypertension,chronic liver failure or heart failure.
  • Unwillingness for endoscopic surgery.
  • Patients younger than 18 years of age.
  • Patients who are unfit for general anesthesia.
  • Previous history of nasal surgery

Key Trial Info

Start Date :

April 25 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

May 1 2026

Estimated Enrollment :

84 Patients enrolled

Trial Details

Trial ID

NCT06887842

Start Date

April 25 2025

End Date

May 1 2026

Last Update

September 11 2025

Active Locations (1)

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kafrelsheikh University Hospitals

Kafrelsheikh, Egypt