Status:
NOT_YET_RECRUITING
DNA Methylation in Brugada Syndrome and Risk of Sudden Cardiac Death
Lead Sponsor:
University of Campania Luigi Vanvitelli
Conditions:
Brugada Syndrome
Sudden Cardiac Death Due to Cardiac Arrhythmia
Eligibility:
All Genders
18+ years
Brief Summary
The goal of this observational study is to evaluate if there are differences in DNA methylation of peripheral blood in patients with Brugada syndrome and healthy subjects. The main question it aims to...
Detailed Description
The Investigators will enroll 10 patients with Brugada syndrome and 10 age and sex matched healthy controls. We will collect 5 mL of peripheral blood and will analyze genome-wide DNA methylation via E...
Eligibility Criteria
Inclusion
- Brugada syndrome was confirmed when the 12-lead ECG showed ST-segment elevation with a type-1 morphology of ≥2 mm in ≥1 right precordial lead either spontaneously or after a provocative drug test (intravenous administration of a Class I antiarrhythmic) in the absence of any structural heart disease.
- \>18 years
- Unrelated patients
Exclusion
- Related patients
- Not type 1 Br patter
Key Trial Info
Start Date :
May 1 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
July 1 2026
Estimated Enrollment :
10 Patients enrolled
Trial Details
Trial ID
NCT06888271
Start Date
May 1 2025
End Date
July 1 2026
Last Update
March 24 2025
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