Status:

COMPLETED

Propolis Lozenges Extract and Their Effect on Salivary Biomarkers and on Oral Health Condition in (19_24) Years Old

Lead Sponsor:

Al-Mustansiriyah University

Conditions:

Plaque Induced Gingivitis

Mouth Diseases

Eligibility:

MALE

19-24 years

Phase:

PHASE1

Brief Summary

The goal of this clinical trial is to test the efficiency of using lozenges containing propolis extract over one week to control gingival inflammation and plaque accumulation by measuring the clinical...

Detailed Description

100 subjects will be enrolled, who show generalized gingivitis (moderate gingivitis) with no Periodontal pocket depth\>3 mm, intact periodontium, and no loss of periodontal attachment), caused by the ...

Eligibility Criteria

Inclusion

  • Age of patients (19\_24) who volunteered to participate.
  • Apparently, good general health. With no systemic diseases.
  • plaque and gingival indices were ranged from (1.1\_2.0)

Exclusion

  • 1\. Individuals with chronic illnesses, immunocompromised individuals, pregnant women, those on contraceptive medications, and breastfeeding mothers.
  • 2\. People who use mouthwash at the moment or any preventive modalities. 3. Those taking anti-inflammatory drugs and antibiotics both during the study and in the final four weeks prior.
  • 4\. Individuals have a history of hypersensitivity to any substance utilized in the current investigation.
  • 5\. Individuals who have undergone a recent tooth extraction. 6. Individuals with Periodontal pocket depth Equal or less than 4 or attachment loss.
  • 7\. Individuals who smoke. 8. Individuals with orthodontic equipment, removable dentures, implants.

Key Trial Info

Start Date :

March 23 2025

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

April 20 2025

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT06888453

Start Date

March 23 2025

End Date

April 20 2025

Last Update

September 24 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Almustansiriyah University

Baghdad, Iraq

Propolis Lozenges Extract and Their Effect on Salivary Biomarkers and on Oral Health Condition in (19_24) Years Old | DecenTrialz