Status:

RECRUITING

Effects of High-Intensity Interval Training on Bone Health in Hong Kong Older Women

Lead Sponsor:

Hong Kong Baptist University

Conditions:

Osteopenia

Eligibility:

FEMALE

60-74 years

Phase:

NA

Brief Summary

Osteoporosis is an age-related disease, characterized by a decreased bone mass and an increased risk of fragility fractures. Osteoporosis leads to increasing mortality, disabilities, morbidity of chro...

Detailed Description

The study will be a randomized controlled trial (RCT) with two groups and three times repeated measures. Data will be collected in a pretest, post-test, and six months after the intervention. The elig...

Eligibility Criteria

Inclusion

  • • 60 to 74 years at the start date of the project
  • diagnosed with osteopenia by DXA scan screening with a BMD at the femoral neck or total hip or lumbar spine between -1 and -2.5 SD T-score below the average values
  • Passing the PAR-Q plus screening or with the physician's approval for readiness to participate in high-intensity exercise
  • Above the average level of 2-mins stepping showing competent aerobic fitness
  • No restriction on physical mobility
  • No cognitive impairment, as determined by the Chinese version of the Mini-Mental Status Examination (i.e., score \< 24)
  • No previous substantial experiences in practicing HIIT. The written informed consent form will be collected from each participant

Exclusion

  • • Severe chronic disease restricting high-intensity exercise
  • Having cognition impairment regarded by specialists
  • checked through medical records at HA Go app platform in the past 6 months, have concurrent medical conditions (e.g., thyrotoxicosis or hyperparathyroidism, Paget's disease, renal disease, diabetes, knee or hip osteoarthritis) and use medications (e.g., corticosteroids, estrogen, thyroxine, thiazide diuretics, or antiretroviral agents) known to affect bone metabolism during past 2 years
  • any condition with osteoporosis, osteoporotic fractures
  • current smoker
  • alcohol 3 or more units per day.

Key Trial Info

Start Date :

October 16 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

October 15 2026

Estimated Enrollment :

48 Patients enrolled

Trial Details

Trial ID

NCT06888544

Start Date

October 16 2024

End Date

October 15 2026

Last Update

March 21 2025

Active Locations (1)

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Bliss District Elderly Community Centre

China, Hong Kong, China, 999077