Status:

RECRUITING

Changes in Perioperative Blood Volume and Fluid Distribution in Patients Undergoing Primary Total Hip Replacement.

Lead Sponsor:

Copenhagen University Hospital, Hvidovre

Conditions:

Hip Arthroplasty Replacement

Eligibility:

All Genders

18+ years

Brief Summary

Clinical assessment of bleeding and calculation of perioperative blood loss do not provide an accurate estimate of blood volume. This makes rational fluid management difficult, which is of high import...

Eligibility Criteria

Inclusion

  • Patients scheduled for an elective total hip arthoplasty (THA) in a standardized fast track setting.
  • Capable of participating in CO-rebreathing measurement
  • Age ≥ 18 years
  • Able to speak and understand Danish
  • Has provided written informed consent.

Exclusion

  • Intraoperative blood loss exceeding 750 mL.
  • Perioperative need for a blood transfusion.
  • Confirmed or suspected coagulopathies.
  • Factors that make CO-rebreathing measurement impossible.
  • Known orthostatic intolerance.
  • American Society of Anesthesiologists physical status (ASA) classification ≥ 4.

Key Trial Info

Start Date :

March 1 2025

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

September 1 2026

Estimated Enrollment :

25 Patients enrolled

Trial Details

Trial ID

NCT06888908

Start Date

March 1 2025

End Date

September 1 2026

Last Update

March 21 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Hvidovre University Hospital

Copenhagen, Denmark, 2960

Changes in Perioperative Blood Volume and Fluid Distribution in Patients Undergoing Primary Total Hip Replacement. | DecenTrialz