Status:

NOT_YET_RECRUITING

Use of Intranasal Midazolam to Reduce Stress and Procedural Pain in Premature Infants During Routine ROP Examination.

Lead Sponsor:

Polish Mother Memorial Hospital Research Institute

Conditions:

Drug Safety

Eligibility:

All Genders

Up to 30 years

Phase:

PHASE1

Brief Summary

The goal of this study is to learn about the safety and effectiveness of intranasal midazolam in newborns and infants born prematurely, undergoing Retinopathy of Prematurity (ROP) screening. The main...

Detailed Description

The aim of this parallel, prospective, nonblinded randomised control trial is to assess the effectiveness and safety of intranasal midazolam administered before ROP screening using the DART™ intranasa...

Eligibility Criteria

Inclusion

  • Newborns qualified for ophthalmologic screening examination to detect retinopathy of prematurity (ROP):
  • a. Newborns/infants born before the 32 weeks of gestation and/or with a birth weight \<1500 g.
  • Obtaining informed consent from a parent/legal guardian.

Exclusion

  • Newborns/infants not qualified for screening ophthalmologic examination (ROP).
  • Newborns/infants clinically unstable, with respiratory disorders/cardiovascular instability before the ophthalmologic examination.
  • Newborns/infants with congenital developmental defects.
  • Newborns/infants receiving analgesic/sedative medications for other reasons.

Key Trial Info

Start Date :

March 24 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

July 6 2025

Estimated Enrollment :

40 Patients enrolled

Trial Details

Trial ID

NCT06889376

Start Date

March 24 2025

End Date

July 6 2025

Last Update

March 21 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Polish Mother's Health Center Institute Rzgowska 281/289, 93-338 Lodz

Lodz, Poland, 93-338