Status:
RECRUITING
Liquid Biopsy Assay of EBUS-TBNA Supernatant Fluid for Diagnosing Lung Cancer
Lead Sponsor:
Barzilai Medical Center
Conditions:
Non Small Cell Lung Cancer
Non Small Cell Lung Cancer (NSCLC)
Eligibility:
All Genders
18+ years
Brief Summary
Background and aim: Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is the gold standard of lung cancer staging, yet up to 15% of procedures produce inadequate samples for...
Detailed Description
Background Lung cancer is the leading cause of cancer deaths. In particular, non-small cell lung cancers (NSCLC) accounts for over 80% of cases. Endobronchial ultrasound-guided transbronchial needle a...
Eligibility Criteria
Inclusion
- adult (age ≥18 years) patients with high suspicion for NSCLC with thoracic lymph nodes involvement (per clinical judgement and imaging studies), planned for an EBUS-TBNA procedure
- Subjects with negative EBUS-TBNA results (no evidence of lymph node involvement by tumor according to histology) who will require surgical resection of the thoracic lymph nodes will comprise the final study group
Exclusion
- Subjects unable or not willing to provide informed consent for study participation.
- Subjects in whom NSCLC will ultimately be ruled out.
- Subjects who will not require surgical resection of thoracic lymph nodes, or who will not undergo such procedure in our Medical Center for any reason
Key Trial Info
Start Date :
January 20 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 31 2025
Estimated Enrollment :
10 Patients enrolled
Trial Details
Trial ID
NCT06889467
Start Date
January 20 2025
End Date
December 31 2025
Last Update
March 26 2025
Active Locations (1)
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1
Barzilai University Medical Center
Ashkelon, Israel