Status:

COMPLETED

A Study of Bimagrumab Alone (LY3985863) and Bimagrumab With Tirzepatide (LY900042) in Healthy Participants

Lead Sponsor:

Eli Lilly and Company

Conditions:

Healthy

Eligibility:

All Genders

18-64 years

Phase:

PHASE1

Brief Summary

The main purpose of this study is to evaluate the body concentration of different forms of bimagrumab, administered alone or with tirzepatide. Participation in the study will last about 4.5 months, in...

Eligibility Criteria

Inclusion

  • Are considered healthy as determined by medical evaluation including medical history and physical examination
  • Have a body mass index (BMI) within the range of 22.0 to 30.0 kilograms per square meter (kg/m2), inclusive

Exclusion

  • Have current or a history of pancreatitis or hepatitis
  • Have a self-reported increase or decrease in body weight, greater than 5 kilograms (kg), within 3 months prior to screening
  • Have uncontrolled high blood pressure
  • Have taken medications or alternative remedies to promote weight loss within 3 months prior to screening

Key Trial Info

Start Date :

March 25 2025

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

September 26 2025

Estimated Enrollment :

125 Patients enrolled

Trial Details

Trial ID

NCT06890611

Start Date

March 25 2025

End Date

September 26 2025

Last Update

October 9 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Fortrea Clinical Research Unit

Dallas, Texas, United States, 75247