Status:
RECRUITING
Cord Blood S100B Protein Concentration in Neonates With Fetal Growth Restriction
Lead Sponsor:
Institute of Mother and Child, Warsaw, Poland
Conditions:
s100b
Hypoxia-Ischemia, Brain
Eligibility:
FEMALE
18+ years
Brief Summary
S100B protein is a biomarker that increases following central nervous system (CNS) damage. Measuring this protein's levels may allow for the early identification of infants at high risk for developmen...
Eligibility Criteria
Inclusion
- Study Group -
- Women with a full-term pregnancy (≥37 weeks of gestation), singleton.
- Pregnancy complicated by FGR.
- Study Group -
Exclusion
- Antenatal (at recruitment):
- Maternal conditions that may affect the blood flow in placental vessels, including smoking, use of illicit stimulant substances, or pregestational diabetes.
- Maternal depression requiring pharmacological treatment (e.g., SSRIs).
- Intrapartum:
- Factors indicating a possible intrauterine infection, such as amniotic fluid leakage for more than 15 hours, spontaneous preterm labor, diagnosed intrauterine infection, or symptoms of infection in the mother.
- Prolonged labor lasting more than 15 hours.
- Control Group - Inclusion Criteria:
- Women with a full-term pregnancy (≥37 weeks of gestation), singleton.
- Pregnancy not complicated by FGR.
- Control Group -
Key Trial Info
Start Date :
June 18 2024
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
March 31 2026
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT06893926
Start Date
June 18 2024
End Date
March 31 2026
Last Update
March 25 2025
Active Locations (1)
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1
Institute of Mother and Child
Warsaw, Poland, 01-211