Status:

RECRUITING

Acute Intra Ocular Pressure Monitoring After Aflibercept 8mg/0.07mL

Lead Sponsor:

Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer

Collaborating Sponsors:

Hôpital d'instruction des armées Sainte-Anne

Conditions:

Macular Diseases

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

In just a few years, intravitreal injections have become a standard method of administration for certain retinal deseases (age-related macular degeneration \[AMD\], diabetic edematous maculopathy or r...

Detailed Description

In order to reduce the frequency of injections in the so-called sub-optimal patients, a "new generation" anti-VEGF will arrive on the market with higher concentrations of active ingredients with a hig...

Eligibility Criteria

Inclusion

  • Patient aged 18 or over;
  • Patient with an indication for Aflibercept 8mg/0.07mL (EYLEA 8mg)
  • Naive or switched patient, i.e. so-called suboptimal responder to anti-VEGF with high injection frequencies
  • Patient with rights to social security
  • Having given free and informed consent before any participation in research.

Exclusion

  • Pregnant or breastfeeding woman
  • Patient under legal protection (guardianship, curatorship, etc.) or legal protection
  • Patient with significant astigmatism distorting the IOP values in applanation
  • Any other reason that, in the opinion of the investigator, could interfere with the evaluation of the study objectives

Key Trial Info

Start Date :

July 8 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

July 1 2027

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT06893965

Start Date

July 8 2025

End Date

July 1 2027

Last Update

November 20 2025

Active Locations (1)

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1

Military Hopsital of Sainte Anne

Toulon, Var, France, 83000