Status:
RECRUITING
ADHERE-LPV Advancing Delivery of High-Quality Evidence-Based Respiratory Efforts in Lung-Protective Ventilation
Lead Sponsor:
University of Minnesota
Conditions:
Ventilation
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
This study is a cluster randomized trial across 10 hospitals, stratified by hospital size (hospitals with greater than 100 mechanically ventilated patients a year will be classified as large, while th...
Eligibility Criteria
Inclusion
- Aged 18 and over
- Requires mechanical ventilation
Exclusion
- The patient opted out of research
- The mode ordered does not require a set tidal volume
- Requires ECMO prior to ICU admission
- Data during the use of ECMO
- Hospitalization was for an elective surgery
- The duration of mechanical ventilation was less than 12 hours (these are not the patients that would benefit from LPV)
- Admission code documentation of Do Not Intubate. While rare, in situations where a patient was intubated but whose preferences are contradictory to the current care, mechanical ventilation is managed differently while undergoing goals of care conversations.
- Height was documented as less than 4 feet given the PBW formula was not validated below this height.
Key Trial Info
Start Date :
July 1 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
July 16 2026
Estimated Enrollment :
1125 Patients enrolled
Trial Details
Trial ID
NCT06895148
Start Date
July 1 2025
End Date
July 16 2026
Last Update
July 9 2025
Active Locations (1)
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1
University of Minnesota
Minneapolis, Minnesota, United States, 55455