Status:
NOT_YET_RECRUITING
Role of USP35 in the Detection of Ferroptosis in Juvenile Autoimmune Hepatitis
Lead Sponsor:
Assiut University
Conditions:
Autoimmune Hepatitis
Eligibility:
All Genders
1-18 years
Brief Summary
1. To evaluate the immunohistochemical expression of USP35 in cases of juvenile autoimmune hepatitis and control cases. 2. To correlate this with the level of necro-inflammation and extent of fibrosis...
Detailed Description
Autoimmune hepatitis (AIH) is a rare and chronic inflammatory disease of the liver of unknown etiology characterized by loss of immune tolerance against liver antigens leading to progressive destructi...
Eligibility Criteria
Inclusion
- Patients aged between one day and 18 years (children)
- patients diagnosed clinically and physically with juvenile autoimmune hepatitis including seronegative autoimmune hepatitis cases
Exclusion
- Cases with inadequate tissue in the paraffin block
- Children with viral hepatitis
- patients above the age of 18 years old
Key Trial Info
Start Date :
November 1 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
January 1 2027
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT06896383
Start Date
November 1 2025
End Date
January 1 2027
Last Update
March 26 2025
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