Status:
NOT_YET_RECRUITING
Latitude - Lateral Lymph Node Attitude Study
Lead Sponsor:
Sahlgrenska University Hospital
Collaborating Sponsors:
Göteborg University
Conditions:
Rectal Neoplasm Malignant
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Patients with advanced rectal cancer can sometimes have suspected tumour affected lymph nodes outside the standard operating field. These patients often receive preoperative treatment before surgery. ...
Detailed Description
Patients with advanced rectal cancer will receive standard care, if lateral lymph nodes exist after neoadjuvant treatment they will be operated accordingly. The focus will be to compare two groups (wi...
Eligibility Criteria
Inclusion
- 18 years or older
- written informed consent
- adenocarcinoma verified tumour below ≤ 8 cm from anal verge measured by rectoscopy and/or MRI
- clinical tumor (cT) stage cT3, cT4a or cT4b on MRI or
- adenocarcinoma verified tumour at any height ≤ 15 cm from anal verge measured by rectoscopy and/or MRI regardless of T/N stage with visible lateral lymph node (according to definition 2.4.2) on pre-therapeutic MRI or PET-CT
Exclusion
- Not biopsy confirmed rectal cancer (adenocarcinoma)
- Recurrent rectal cancer
- Age below 18
- Participation in other trials in conflict with the protocol and end-points of the Latitude study
- No informed consent
Key Trial Info
Start Date :
September 15 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
February 1 2034
Estimated Enrollment :
1000 Patients enrolled
Trial Details
Trial ID
NCT06896578
Start Date
September 15 2025
End Date
February 1 2034
Last Update
August 8 2025
Active Locations (1)
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1
Dept. of Surgery, Sahlgrenska University Hospital/Ostra
Gothenburg, Sweden, SE 416 85