Status:
ACTIVE_NOT_RECRUITING
Implantation of Cartilage Mini-grafts Made From Donor Cells to Treat Chondral Lesions of the Knee
Lead Sponsor:
Vanarix SA
Conditions:
Cartilage Repair
Eligibility:
All Genders
18+ years
Phase:
PHASE1
PHASE2
Brief Summary
The purpose of this study is to investigate the safety and feasibility of implanting allogeneic cartilage mini-grafts (or allogenic Cartibeads) into cartilage defects in the knee. Allogeneic Cartibea...
Eligibility Criteria
Inclusion
- Key inclusion criteria:
- Symptomatic cartilage lesion(s) of the femorotibial and/or patellofemoral compartments (includes isolated, multiple and kissing lesions)
- Cartilage lesion(s) ≥ 1 cm2 and ≤ 10 cm2
- ICRS grade 3 or 4
- Aged over 18 years
- Key exclusion criteria
- Inability to undergo MRI
- Cartilage specific surgery within 6 months from baseline
- Cartilage therapeutic injection within 3 months from baseline
- Chronic inflammatory arthritis and/or infectious arthritis
Exclusion
Key Trial Info
Start Date :
June 17 2024
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 1 2025
Estimated Enrollment :
10 Patients enrolled
Trial Details
Trial ID
NCT06897111
Start Date
June 17 2024
End Date
July 1 2025
Last Update
March 26 2025
Active Locations (4)
Enter a location and click search to find clinical trials sorted by distance.
1
Center for Sports Medicine and Exercise, Hirslanden Clinique La Colline
Geneva, Canton of Geneva, Switzerland, 1206
2
Geneva University Hospitals (HUG)
Geneva, Canton of Geneva, Switzerland, 1211
3
Balgrist University Hospital (BUH)
Zurich, Canton of Zurich, Switzerland, 8008
4
Ente Ospedaliero Cantonale (EOC)
Lugano, Canton Ticino, Switzerland, 6962